• A dope, a person who is stupid
• Dope, adj.: cool, nice, awesome; popularized by hip hop culture. e.g. That beat is dope.
• Discrete optimized protein energy, a method of assessing homology models in protein structure prediction
• Dope (band), an industrial rock band based in New York
  • Edsel Dope, the lead singer of the band
  • Angel Bartolotta, the drummer of the band
• Dopant, an impurity added to a substance to alter its properties
• The Straight Dope, a newspaper column
• Dopefish, a type of fish used as an in-joke in the Commander Keen universe and games made after
• Cannabis, cocaine, heroin, or methamphetamine, depending on region and time-period
• Aircraft dope, a substance painted onto fabric-covered aircraft to tauten the skin
• Pipe dope, a slang term in plumbing for a chemical sealant applied to pipe threads to ensure a leakproof and pressure-tight seal
• Peg dope
• Dope (comic), by Sax Rohmer and Trina Robbins
• Dope (film), the bootlegged version of Shot of Love, a 2003 film
• Dope(s), a voting unit popularized by the underground hip hop website DopeTracks, also referred to as Dope Points
• The Inevitable Return Of The Great White Dope, a song by The Bloodhound Gang

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